Article
RecG Directs DNA Synthesis during Double-Strand Break Repair.
PLoS genetics - 1 Feb 2016
Azeroglu Benura, Mawer Julia S P, Cockram Charlotte A, White Martin A, Hasan A M Mahedi, Filatenkova Milana, Leach David R F
Abstract excerpt
Homologous recombination provides a mechanism of DNA double-strand break repair (DSBR) that requires an intact, homologous template for DNA synthesis. When DNA synthesis associated with DSBR is convergent, the broken DNA strands are replaced and repair is accurate. However, if divergent DNA synthesis is established, over-replication of flanking DNA may occur with deleterious consequences. The RecG protein of...
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