Article
RecG helicase promotes DNA double-strand break repair.
Molecular microbiology - 1 Apr 2004
Meddows Tom R, Savory Andrew P, Lloyd Robert G
Abstract excerpt
Double-strand breaks pose a major threat to the genome and must be repaired accurately if structural and functional integrity are to be preserved. This is usually achieved via homologous recombination, which enables the ends of a broken DNA molecule to engage an intact duplex and prime synthesis of the DNA needed for repair. In Escherichia coli, repair relies on the RecBCD and RecA proteins, the combined ability...
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