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Article

RecQ helicase and RecJ nuclease provide complementary functions to resect DNA for homologous recombination.

Proceedings of the National Academy of Sciences of the United States of America - 2 Dec 2014

Morimatsu Katsumi, Kowalczykowski Stephen C

Abstract excerpt

Recombinational DNA repair by the RecF pathway of Escherichia coli requires the coordinated activities of RecA, RecFOR, RecQ, RecJ, and single-strand DNA binding (SSB) proteins. These proteins facilitate formation of homologously paired joint molecules between linear double-stranded (dsDNA) and supercoiled DNA. Repair starts with resection of the broken dsDNA by RecQ, a 3'→5' helicase, RecJ, a 5'→3' exonuclease,...

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Source

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Identifiers

PMID: 25411316
DOI: 10.1073/pnas.1420009111
PMCID: PMC4260596

Genes

SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RecQ helicase and RecJ nuclease provide complementary functions to resect DNA for homologous recombination.PMID 25411316Read ↗

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