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Article

NDRG1 regulates neutral lipid metabolism in breast cancer cells.

Breast cancer research : BCR - 14 Jun 2018

Sevinsky Christopher J, Khan Faiza, Kokabee Leila, Darehshouri Anza, Maddipati Krishna Rao, Conklin Douglas S

Abstract excerpt

BACKGROUND: Altered lipid metabolism is an emerging hallmark of aggressive breast cancers. The N-myc downstream regulated gene (NDRG1) gene plays a critical role in peripheral nervous system myelination, as inactivating mutations cause severe demyelinating neuropathy. In breast cancer, elevated NDRG1 expression has been linked to clinical outcomes, but its functional role in breast cancer physiology has remained...

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Identifiers

PMID: 29898756
DOI: 10.1186/s13058-018-0980-4
PMCID: PMC6001025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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