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Article

NDRG1 in Cancer: A Suppressor, Promoter, or Both?

22 Nov 2022

Abstract excerpt

N-myc downregulated gene-1 (NDRG1) has been variably reported as a metastasis suppressor, a biomarker of poor outcome, and a facilitator of disease progression in a range of different cancers. NDRG1 is poorly understood in cancer due to its context-dependent and pleiotropic functions. Within breast cancer, NDRG1 is reported to be either a facilitator of, or an inhibitor of tumour progression and metastasis. The...

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PMID: 36497221
DOI: 10.3390/cancers14235739

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