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NDRGs in Breast Cancer: A Review and In Silico Analysis

29 Mar 2024

Abstract excerpt

The N-myc downstream regulated gene family (NDRGs) includes four members: NDRG1, NDRG2, NDRG3, and NDRG4. These members exhibit 53–65% amino acid identity. The role of NDRGs in tumor growth and metastasis appears to be tumor- and context-dependent. While many studies have reported that these family members have tumor suppressive roles, recent studies have demonstrated that NDRGs, particularly NDRG1 and NDRG2,...

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PMID: 38611020
DOI: 10.3390/cancers16071342

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