Article
A joint analysis of metabolomics and genetics of breast cancer.
Breast cancer research : BCR - 5 Aug 2014
Tang Xiaohu, Lin Chao-Chieh, Spasojevic Ivan, Iversen Edwin S, Chi Jen-Tsan, Marks Jeffrey R
Abstract excerpt
INTRODUCTION: Remodeling of cellular metabolism appears to be a consequence and possibly a cause of oncogenic transformation in human cancers. Specific aspects of altered tumor metabolism may be amenable to therapeutic intervention and could be coordinated with other targeted therapies. In breast cancer, the genetic landscape has been defined most comprehensively in efforts such as The Cancer Genome Atlas (TCGA)....
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