Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells

8 Jun 2018

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomedical Ethics and Regulation
Share to CRISPR and Genetic Engineering
Share to Pluripotent Stem Cells Research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 29892062
DOI: 10.1038/s41591-018-0050-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cellsPMID 29892062Read ↗

P53 toxicity is a hurdle to CRISPR/CAS9 screening and engineering in human pluripotent stem cellsSemantic proximity Read ↗

Genome Editing in Human Pluripotent Stem Cells: Approaches, Pitfalls, and Solutions.Semantic proximity Read ↗

Engineering Human Stem Cell Lines with Inducible Gene Knockout using CRISPR/Cas9Semantic proximity Read ↗

Crispr-mediated Gene Targeting of Human Induced Pluripotent Stem Cells.Semantic proximity Read ↗

A high efficiency precision genome editing method with CRISPR in iPSCsSemantic proximity Read ↗

Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus.Semantic proximity Read ↗

Δ133p53 represses p53-inducible senescence genes and enhances the generation of human induced pluripotent stem cellsSemantic proximity Read ↗

Cas9 activates the p53 pathway and selects for p53-inactivating mutations.Semantic proximity Read ↗

CRISPR‐Cas9‐Based Genome Editing of Human Induced Pluripotent Stem CellsSemantic proximity Read ↗

Genome-Scale CRISPR Screening Identifies Novel Human Pluripotent Gene NetworksSemantic proximity Read ↗

Comprehensive Protocols for CRISPR/Cas9-based Gene Editing in Human Pluripotent Stem Cells.Semantic proximity Read ↗

CRISPR enriches for cells with mutations in a p53-related interactome, and this can be inhibitedSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.