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Article

The ApoE gene is related with exceptional longevity: a systematic review and meta-analysis.

Rejuvenation research - 1 Feb 2015

Garatachea Nuria, Marín Pedro J, Santos-Lozano Alejandro, Sanchis-Gomar Fabian, Emanuele Enzo, Lucia Alejandro

Abstract excerpt

The objective of this meta-analysis was to determine the association of the apolipoprotein E (ApoE) gene with exceptional longevity (EL) (i.e., reaching 100+ years) by identifying possible unequal distribution of alleles/genotypes in the common variants ε2, ε3, and ε4 among centenarians and younger population. The association of ApoE with EL was analyzed in a total of 2776 centenarians (cases) and 11,941 younger...

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Identifiers

PMID: 25385258
DOI: 10.1089/rej.2014.1605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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