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Article

Elevation of the TP53 isoform Δ133p53β in glioblastomas: an alternative to mutant p53 in promoting tumor development.

The Journal of pathology - 1 Sept 2018

Kazantseva Marina, Eiholzer Ramona A, Mehta Sunali, Taha Ahmad, Bowie Sara, Roth Imogen, Zhou Jean, Joruiz Sebastien M, Royds Janice A, Hung Noelyn A, Slatter Tania L, Braithwaite Antony W

Abstract excerpt

As tumor protein 53 (p53) isoforms have tumor-promoting, migration, and inflammatory properties, this study investigated whether p53 isoforms contributed to glioblastoma progression. The expression levels of full-length TP53α (TAp53α) and six TP53 isoforms were quantitated by RT-qPCR in 89 glioblastomas and correlated with TP53 mutation status, tumor-associated macrophage content, and various immune cell markers....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29888503
DOI: 10.1002/path.5111
PMCID: PMC6120556

Genes

CCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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