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Aging in the Brain: New Roles of Epigenetics in Cognitive Decline

7 Jun 2018

Abstract excerpt

Gene expression in the aging brain depends on transcription signals generated by senescent physiology, interacting with genetic and epigenetic programs. In turn, environmental factors influence epigenetic mechanisms, such that an epigenetic-environmental link may contribute to the accumulation of cellular damage, susceptibility or resilience to stressors, and variability in the trajectory of age-related cognitive...

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PMID: 29877135
DOI: 10.1177/1073858418780971

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