Article
Epigenetic mechanisms in Alzheimer's disease.
Neurobiology of aging - 1 Jul 2011
Mastroeni Diego, Grover Andrew, Delvaux Elaine, Whiteside Charisse, Coleman Paul D, Rogers Joseph
Abstract excerpt
Epigenetic modifications help orchestrate sweeping developmental, aging, and disease-causing changes in phenotype by altering transcriptional activity in multiple genes spanning multiple biologic pathways. Although previous epigenetic research has focused primarily on dividing cells, particularly in cancer, recent studies have shown rapid, dynamic, and persistent epigenetic modifications in neurons that have...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
