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Article

Epigenetic control of aging.

Antioxidants & redox signaling - 15 Jan 2011

Muñoz-Najar Ursula, Sedivy John M

Abstract excerpt

Organismal aging and longevity are influenced by many complex interacting factors. Epigenetics has recently emerged as another possible determinant of aging. Here, we review some of the epigenetic pathways that contribute to cellular senescence and age-associated phenotypes. Strategies aimed to reverse age-linked epigenetic alterations may lead to the development of new therapeutic interventions to delay or...

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Identifiers

PMID: 20518699
DOI: 10.1089/ars.2010.3250
PMCID: PMC3014766

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