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Epigenetic regulation of aging: implications for interventions of aging and diseases

6 Nov 2022

Abstract excerpt

Aging is accompanied by the decline of organismal functions and a series of prominent hallmarks, including genetic and epigenetic alterations. These aging-associated epigenetic changes include DNA methylation, histone modification, chromatin remodeling, non-coding RNA (ncRNA) regulation, and RNA modification, all of which participate in the regulation of the aging process, and hence contribute to aging-related...

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PMID: 36336680
DOI: 10.1038/s41392-022-01211-8

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