Article
Advances in epigenetics and epigenomics for neurodegenerative diseases.
Current neurology and neuroscience reports - 1 Oct 2011
Qureshi Irfan A, Mehler Mark F
Abstract excerpt
In the post-genomic era, epigenetic factors-literally those that are "over" or "above" genetic ones and responsible for controlling the expression and function of genes-have emerged as important mediators of development and aging; gene-gene and gene-environmental interactions; and the pathophysiology of complex disease states. Here, we provide a brief overview of the major epigenetic mechanisms (ie, DNA...
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