Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of different analysis pipelines for the detection of HIV-1 minority resistant variants.

PloS one - 1 Jan 2018

Perrier Marine, Désiré Nathalie, Storto Alexandre, Todesco Eve, Rodriguez Christophe, Bertine Mélanie, Le Hingrat Quentin, Visseaux Benoit, Calvez Vincent, Descamps Diane, Marcelin Anne-Geneviève, Charpentier Charlotte

Abstract excerpt

OBJECTIVE: Reliable detection of HIV minority resistant variants (MRVs) requires bioinformatics analysis with specific algorithms to obtain good quality alignments. The aim of this study was to analyze ultra-deep sequencing (UDS) data using different analysis pipelines. METHODS: HIV-1 protease, reverse transcriptase (RT) and integrase sequences from antiretroviral-naïve patients were obtained using GS-Junior®...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to HIV Integrase

Share to HIV Protease

Share to HIV Reverse Transcriptase

Share to Microbial Sensitivity Tests

Source

Open in PubMed Open full text

Identifiers

PMID: 29856864
DOI: 10.1371/journal.pone.0198334
PMCID: PMC5983569

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of different analysis pipelines for the detection of HIV-1 minority resistant variants.PMID 29856864Read ↗

Comparison of ultra-deep versus Sanger sequencing detection of minority mutations on the HIV-1 drug resistance interpretations after virological failureSemantic proximity Read ↗

Minority resistant variants are also present in HIV-2-infected antiretroviral-naive patients.Semantic proximity Read ↗

Comparison of sequencing methods and data processing pipelines for whole genome sequencing and minority single nucleotide variant (mSNV) analysis during an influenza A/H5N8 outbreak.Semantic proximity Read ↗

Performance comparison of next generation sequencing analysis pipelines for HIV-1 drug resistance testing.Semantic proximity Read ↗

Minority resistant HIV-1 variants and the response to first-line NNRTI therapy.Semantic proximity Read ↗

Bioinformatic data processing pipelines in support of next‐generation sequencing‐based HIV drug resistance testing: the Winnipeg ConsensusSemantic proximity Read ↗

Evaluation of Automatic Analysis of Ultradeep Pyrosequencing Raw Data to Determine Percentages of HIV Resistance Mutations in Patients Followed-Up in Hospital.Semantic proximity Read ↗

Shall I trust the report? Variable performance of Sanger sequencing revealed by deep sequencing on HIV drug resistance mutation detection.Semantic proximity Read ↗

Assessment of Transmitted HIV-1 Drug Resistance Mutations Using Ultra- Deep Pyrosequencing in a Turkish Cohort.Semantic proximity Read ↗

Comparison of HIV-1 drug-resistance genotyping by ultra-deep sequencing and sanger sequencing using clinical samples.Semantic proximity Read ↗

Identification of minority resistance mutations in the HIV-1 integrase coding region using next generation sequencing.Semantic proximity Read ↗

Performance comparison of deep sequencing platforms for detecting HIV-1 variants in the pol gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.