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Article

Shall I trust the report? Variable performance of Sanger sequencing revealed by deep sequencing on HIV drug resistance mutation detection.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Apr 2020

Chen Nan-Yu, Kao Shu-Wei, Liu Zhuo-Hao, Wu Ting-Shu, Tsai Chia-Lung, Lin Hsi-Hsun, Wong Wing-Wai, Chang Yea-Yuan, Chen Shu-Sheng, Ku Stephane Wen-Wei

Abstract excerpt

BACKGROUND: The clinical utilisation of deep sequencing in HIV treatment has been hindered due to its unknown correlation with standard Sanger genotyping and the undetermined value of minority drug resistance mutation (DRM) detection. OBJECTIVES: To compare deep sequencing performance to standard Sanger genotyping with clinical samples, in an effort to delineate the correlation between the results from the two...

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Identifiers

PMID: 32061862
DOI: 10.1016/j.ijid.2020.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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