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Article

GWAS reveals loci associated with velopharyngeal dysfunction.

Scientific reports - 31 May 2018

Chernus Jonathan, Roosenboom Jasmien, Ford Matthew, Lee Myoung Keun, Emanuele Beth, Anderton Joel, Hecht Jacqueline T, Padilla Carmencita, Deleyiannis Frederic W B, Buxo Carmen J, Feingold Eleanor, Leslie Elizabeth J, Shaffer John R, Weinberg Seth M, Marazita Mary L

Abstract excerpt

Velopharyngeal dysfunction (VPD) occurs when the muscular soft palate (velum) and lateral pharyngeal walls are physically unable to separate the oral and nasal cavities during speech production leading to hypernasality and abnormal speech reduction. Because VPD is often associated with overt or submucous cleft palate, it could be present as a subclinical phenotype in families with a history of orofacial clefting....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29855589
DOI: 10.1038/s41598-018-26880-w
PMCID: PMC5981322

Genes

BNC2
FREM1
TFRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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