Article
Genome-wide association analysis of Vogt-Koyanagi-Harada syndrome identifies two new susceptibility loci at 1p31.2 and 10q21.3.
Nature genetics - 1 Sept 2014
Hou Shengping, Du Liping, Lei Bo, Pang Chi Pui, Zhang Meifen, Zhuang Wenjuan, Zhang Minglian, Huang Lulin, Gong Bo, Wang Meilin, Zhang Qi, Hu Ke, Zhou Qingyun, Qi Jian, Wang Chaokui, Tian Yuan, Ye Zi, Liang Liang, Yu Hongsong, Li Hong, Zhou Yan, Cao Qingfeng, Liu Yunjia, Bai Lin, Liao Dan, Kijlstra Aize, Xu Jianfeng, Yang Zhenglin, Yang Peizeng
Abstract excerpt
To identify new genetic risk factors for Vogt-Koyanagi-Harada (VKH) syndrome, we conducted a genome-wide association study of 2,208,258 SNPs in 774 cases and 2,009 controls with follow-up in a collection of 415 cases and 2,006 controls and a further collection of 349 cases and 1,588 controls from a Han Chinese population. We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141,...
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