Article

Trio-based GWAS reveals novel loci associated with different forms of isolated cleft lip

2026-03-17

Abstract excerpt

<h4>ABSTRACT</h4> Orofacial clefts (OFCs) are the most common craniofacial birth defect and comprise a diverse group of traits with complex and heterogeneous etiologies. Genetic studies of OFCs typically approach this diversity by stratifying cases into broad diagnostic classes, including cleft lip (CL), cleft palate (CP), and cleft lip with palate (CLP). Although this strategy has yielded important insights into...

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Literature Corpus work: 2a10d6cf-1352-5f11-aadc-3ccef72b5528
DOI: 10.64898/2026.03.15.26348427

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