Article

Trio-based GWAS identifies novel associations and subtype-specific risk factors for cleft palate

2023-03-05

Abstract excerpt

Orofacial clefts (OFCs) are the most common craniofacial birth defects and are often categorized into two etiologically distinct groups: cleft lip with or without cleft palate (CL/P) and isolated cleft palate (CP). CP is highly heritable, but there are still relatively few established genetic risk factors associated with its occurrence compared to CL/P. Historically, CP has been studied as a single phenotype despi...

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Literature Corpus work: d76b6e25-f2f7-5bb1-b600-6ac9262c82e4
DOI: 10.1101/2023.03.01.23286642

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