Article
Replication of 13q31.1 association in nonsyndromic cleft lip with cleft palate in Europeans.
American journal of medical genetics. Part A - 1 May 2015
Jia Zhonglin, Leslie Elizabeth J, Cooper Margaret E, Butali Azeez, Standley Jennifer, Rigdon Jennifer, Suzuki Satoshi, Gongorjav Ayana, Shonkhuuz T Enkhtur, Natsume Nagato, Shi Bing, Marazita Mary L, Murray Jeffrey C
Abstract excerpt
Genome wide association (GWA) studies have successfully identified at least a dozen loci associated with orofacial clefts. However, these signals may be unique to specific populations and require replication to validate and extend findings as a prelude to etiologic SNP discovery. We attempted to replicate the findings of a recent meta-analysis of orofacial cleft GWA studies using four different ancestral...
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