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Article

Metaphase kinetochore movements are regulated by kinesin-8 motors and microtubule dynamic instability.

Molecular biology of the cell - 1 Jun 2018

Klemm Anna H, Bosilj Agneza, Gluncˇic Matko, Pavin Nenad, Tolic Iva M

Abstract excerpt

During metaphase, sister chromatids are connected to microtubules extending from the opposite spindle poles via kinetochores to protein complexes on the chromosome. Kinetochores congress to the equatorial plane of the spindle and oscillate around it, with kinesin-8 motors restricting these movements. Yet, the physical mechanism underlying kinetochore movements is unclear. We show that kinetochore movements in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29851559
DOI: 10.1091/mbc.E17-11-0667
PMCID: PMC5994901

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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