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Article

Abnormalities of age-related T cell senescence in Parkinson’s disease

28 May 2018

Abstract excerpt

BACKGROUND: A wealth of evidence implicates both central and peripheral immune changes as contributing to the pathogenesis of Parkinson's disease (PD). It is critical to better understand this aspect of PD given that it is a tractable target for disease-modifying therapy. Age-related changes are known to occur in the immune system (immunosenescence) and might be of particular relevance in PD given that its...

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PMID: 29807534
DOI: 10.1186/s12974-018-1206-5

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