Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD4+ regulatory and effector/memory T cell subsets profile motor dysfunction in Parkinson's disease.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology - 1 Dec 2012

Saunders Jessica A Hutter, Estes Katherine A, Kosloski Lisa M, Allen Heather E, Dempsey Kathryn M, Torres-Russotto Diego R, Meza Jane L, Santamaria Pamela M, Bertoni John M, Murman Daniel L, Ali Hesham H, Standaert David G, Mosley R Lee, Gendelman Howard E

Abstract excerpt

Animal models and clinical studies have linked the innate and adaptive immune system to the pathology of Parkinson's disease (PD). Despite such progress, the specific immune responses that influence disease progression have eluded investigators. Herein, we assessed relationships between T cell phenotype and function with PD progression. Peripheral blood lymphocytes from two separate cohorts, a discovery cohort...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Cell Count
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-6

Share to Monocytes

Share to Movement Disorders

Share to Parkinson Disease

Share to T-Lymphocyte Subsets

Share to Tumor Necrosis Factor Receptor Superfamily, Member 7

Source

Open in PubMed Open full text

Identifiers

PMID: 23054369
DOI: 10.1007/s11481-012-9402-z
PMCID: PMC3515774

Genes

FAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD4+ regulatory and effector/memory T cell subsets profile motor dysfunction in Parkinson's disease.PMID 23054369Read ↗

Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in femalesSemantic proximity Read ↗

Abnormal B-Cell and Tfh-Cell Profiles in Patients With Parkinson DiseaseSemantic proximity Read ↗

Parkinson’s disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patientsSemantic proximity Read ↗

Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signaturesSemantic proximity Read ↗

Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signaturesSemantic proximity Read ↗

Adaptive Immunity and Parkinson's Disease.Semantic proximity Read ↗

Mapping the peripheral immune landscape of Parkinson’s disease patients with single-cell sequencingSemantic proximity Read ↗

T lymphocyte senescence is attenuated in Parkinson’s diseaseSemantic proximity Read ↗

Immunological shifts during early-stage Parkinson’s disease identified with DNA methylation data on longitudinally collected blood samplesSemantic proximity Read ↗

Peripheral blood lymphocyte phenotypes in Alzheimer and Parkinson's diseases.Semantic proximity Read ↗

Impaired migratory phenotype of CD4+ T cells in Parkinson’s diseaseSemantic proximity Read ↗

Inflammation and regulatory T cell genes are differentially expressed in peripheral blood mononuclear cells of Parkinson’s disease patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.