Article
Cytomegalovirus and immune senescence: culprit or innocent bystander?
Experimental gerontology - 1 Nov 2009
Karrer Urs, Mekker Andrea, Wanke Kerstin, Tchang Vincent, Haeberli Lea
Abstract excerpt
Immune senescence may be defined as the age-related reduction and dysregulation of immune function, and has been associated with increased incidence and severity of infectious diseases and with poor efficacy of prophylactic vaccines in the elderly. Several studies have demonstrated that persistent infections with Herpes viruses in general and Cytomegalovirus (CMV) in particular have a profound influence on subset...
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