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Aging, cellular senescence and Parkinson's disease

2 Feb 2025

Abstract excerpt

Parkinson's disease (PD) is the most common neurodegenerative movement disorder, affecting 1-2% of people over age 65. The risk of developing PD dramatically increases with advanced age, indicating that aging is likely a driving factor in PD neuropathogenesis. Several age-associated biological changes are also hallmarks of PD neuropathology, including mitochondrial dysfunction, oxidative stress, and...

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PMID: 39973488
DOI: 10.1177/1877718x251316552

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