Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

T lymphocyte senescence is attenuated in Parkinson’s disease

13 Oct 2021

Abstract excerpt

Abstract Background Immune involvement is well-described in Parkinson’s disease (PD), including an adaptive T lymphocyte response. Given the increasing prevalence of Parkinson’s disease in older age, age-related dysregulation of T lymphocytes may be relevant in this disorder, and we have previously observed changes in age-associated CD8+ T cell subsets in mid-stage PD. This study aimed to further characterise T...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Neuroinflammation and Neurodegeneration Mechanisms
Share to Psoriasis: Treatment and Pathogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34645462
DOI: 10.1186/s12974-021-02287-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

T lymphocyte senescence is attenuated in Parkinson’s diseasePMID 34645462Read ↗

Abnormalities of age-related T cell senescence in Parkinson’s diseaseSemantic proximity Read ↗

CD8+ T Cell Senescence: Lights and Shadows in Viral Infections, Autoimmune Disorders and CancerSemantic proximity Read ↗

Aging, cellular senescence and Parkinson's diseaseSemantic proximity Read ↗

Adaptive Immunity and Parkinson's Disease.Semantic proximity Read ↗

CD4+ regulatory and effector/memory T cell subsets profile motor dysfunction in Parkinson's disease.Semantic proximity Read ↗

Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in femalesSemantic proximity Read ↗

Telomerase reverse transcriptase and neurodegenerative diseasesSemantic proximity Read ↗

Abnormal B-Cell and Tfh-Cell Profiles in Patients With Parkinson DiseaseSemantic proximity Read ↗

Pathologic T cell immunosenescence drives the development of age-associated autoimmune peripheral neuropathySemantic proximity Read ↗

The Role of Immune Dysfunction in Parkinson's Disease DevelopmentSemantic proximity Read ↗

Telomerase deficiency reflects age-associated changes in CD4+ T cellsSemantic proximity Read ↗

Impaired migratory phenotype of CD4+ T cells in Parkinson’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.