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Article

Adaptive genome duplication affects patterns of molecular evolution in Saccharomyces cerevisiae.

PLoS genetics - 1 May 2018

Fisher Kaitlin J, Buskirk Sean W, Vignogna Ryan C, Marad Daniel A, Lang Gregory I

Abstract excerpt

Genome duplications are important evolutionary events that impact the rate and spectrum of beneficial mutations and thus the rate of adaptation. Laboratory evolution experiments initiated with haploid Saccharomyces cerevisiae cultures repeatedly experience whole-genome duplication (WGD). We report recurrent genome duplication in 46 haploid yeast populations evolved for 4,000 generations. We find that WGD confers...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 29799840
DOI: 10.1371/journal.pgen.1007396
PMCID: PMC5991770

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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