Article
Experimental evolution of the model eukaryote Saccharomyces cerevisiae yields insight into the molecular mechanisms underlying adaptation.
Current opinion in microbiology - 1 Dec 2015
Voordeckers Karin, Verstrepen Kevin J
Abstract excerpt
Understanding how changes in DNA drive the emergence of new phenotypes and fuel evolution remains a major challenge. One major hurdle is the lack of a fossil record of DNA that allows linking mutations to phenotypic changes. However, the emergence of high-throughput sequencing technologies now al...
Topics
- Adaptation, Physiological
- Directed Molecular Evolution
- Evolution, Molecular
- Gene Duplication
- Genome, Fungal
- High-Throughput Nucleotide Sequencing
- Mutation
- Phenotype
- Saccharomyces cerevisiae
- Sequence Analysis, DNA