Article
Genome Mutational and Transcriptional Hotspots Are Traps for Duplicated Genes and Sources of Adaptations.
Genome biology and evolution - 1 May 2017
Fares Mario A, Sabater-Muñoz Beatriz, Toft Christina
Abstract excerpt
Gene duplication generates new genetic material, which has been shown to lead to major innovations in unicellular and multicellular organisms. A whole-genome duplication occurred in the ancestor of Saccharomyces yeast species but 92% of duplicates returned to single-copy genes shortly after duplication. The persisting duplicated genes in Saccharomyces led to the origin of major metabolic innovations, which have...
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