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Emerging patterns of somatic mutations in cancer.

Nature reviews. Genetics - 1 Oct 2013

Watson Ian R, Takahashi Koichi, Futreal P Andrew, Chin Lynda

Abstract excerpt

Recent advances in technological tools for massively parallel, high-throughput sequencing of DNA have enabled the comprehensive characterization of somatic mutations in a large number of tumour samples. In this Review, we describe recent cancer genomic studies that have assembled emerging views of the landscapes of somatic mutations through deep-sequencing analyses of the coding exomes and whole genomes in...

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Exome
Genome, Human
Genomics
High-Throughput Nucleotide Sequencing
Mutation
Mutation Rate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

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PMID: 24022702
DOI: 10.1038/nrg3539
PMCID: PMC4014352

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