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Article

Quantitative imaging of chromatin decompaction in living cells.

Molecular biology of the cell - 15 Jul 2018

Dultz Elisa, Mancini Roberta, Polles Guido, Vallotton Pascal, Alber Frank, Weis Karsten

Abstract excerpt

Chromatin organization is highly dynamic and regulates transcription. Upon transcriptional activation, chromatin is remodeled and referred to as "open," but quantitative and dynamic data of this decompaction process are lacking. Here, we have developed a quantitative high resolution-microscopy assay in living yeast cells to visualize and quantify chromatin dynamics using the GAL7-10-1 locus as a model system....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29771637
DOI: 10.1091/mbc.E17-11-0648
PMCID: PMC6080713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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