Article
Behaviors of nucleosomes with mutant histone H4s in euchromatic domains of living human cells.
Histochemistry and cell biology - 1 Jul 2024
Semeigazin Adilgazy, Iida Shiori, Minami Katsuhiko, Tamura Sachiko, Ide Satoru, Higashi Koichi, Toyoda Atsushi, Kurokawa Ken, Maeshima Kazuhiro
Abstract excerpt
Since Robert Feulgen first stained DNA in the cell, visualizing genome chromatin has been a central issue in cell biology to uncover how chromatin is organized and behaves in the cell. To approach this issue, we have developed single-molecule imaging of nucleosomes, a basic unit of chromatin, to unveil local nucleosome behavior in living cells. In this study, we investigated behaviors of nucleosomes with various...
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