Article
Myosin1D is an evolutionarily conserved regulator of animal left-right asymmetry.
Nature communications - 16 May 2018
Juan Thomas, Géminard Charles, Coutelis Jean-Baptiste, Cerezo Delphine, Polès Sophie, Noselli Stéphane, Fürthauer Maximilian
Abstract excerpt
The establishment of left-right (LR) asymmetry is fundamental to animal development, but the identification of a unifying mechanism establishing laterality across different phyla has remained elusive. A cilia-driven, directional fluid flow is important for symmetry breaking in numerous vertebrates, including zebrafish. Alternatively, LR asymmetry can be established independently of cilia, notably through the...
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