Article
Common and Rare Variants Genetic Association Analysis of Cigarettes per Day Among Ever-Smokers in Chronic Obstructive Pulmonary Disease Cases and Controls.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 21 May 2019
Lutz Sharon M, Frederiksen Brittni, Begum Ferdouse, McDonald Merry-Lynn N, Cho Michael H, Hobbs Brian D, Parker Margaret M, DeMeo Dawn L, Hersh Craig P, Ehringer Marissa A, Young Kendra, Jiang Lai, Foreman Marilyn G, Kinney Greg L, Make Barry J, Lomas David A, Bakke Per, Gulsvik Amund, Crapo James D, Silverman Edwin K, Beaty Terri H, Hokanson John E
Abstract excerpt
INTRODUCTION: Cigarette smoking is a major environmental risk factor for many diseases, including chronic obstructive pulmonary disease (COPD). There are shared genetic influences on cigarette smoking and COPD. Genetic risk factors for cigarette smoking in cohorts enriched for COPD are largely unknown. METHODS: We performed genome-wide association analyses for average cigarettes per day (CPD) across the Genetic...
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