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RNA sequencing identifies novel non-coding RNA and exon-specific effects associated with cigarette smoking

6 Oct 2017

Abstract excerpt

BACKGROUND: Cigarette smoking is the leading modifiable risk factor for disease and death worldwide. Previous studies quantifying gene-level expression have documented the effect of smoking on mRNA levels. Using RNA sequencing, it is possible to analyze the impact of smoking on complex regulatory phenomena (e.g. alternative splicing, differential isoform usage) leading to a more detailed understanding of the...

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PMID: 28985737
DOI: 10.1186/s12920-017-0295-9

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