Genetic variants and risk of lung cancer in never smokers: a genome-wide association study.

doi:10.1016/S1470-2045(10)70042-5

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Article

Genetic variants and risk of lung cancer in never smokers: a genome-wide association study.

The Lancet. Oncology - 1 Apr 2010

Li Yafei, Sheu Chau-Chyun, Ye Yuanqing, de Andrade Mariza, Wang Liang, Chang Shen-Chih, Aubry Marie C, Aakre Jeremiah A, Allen Mark S, Chen Feng, Cunningham Julie M, Deschamps Claude, Jiang Ruoxiang, Lin Jie, Marks Randolph S, Pankratz V Shane, Su Li, Li Yan, Sun Zhifu, Tang Hui, Vasmatzis George, Harris Curtis C, Spitz Margaret R, Jen Jin, Wang Renyi, Zhang Zuo-Feng, Christiani David C, Wu Xifeng, Yang Ping

Abstract excerpt

BACKGROUND: Lung cancer in individuals who have never smoked tobacco products is an increasing medical and public-health issue. We aimed to unravel the genetic basis of lung cancer in never smokers. METHODS: We did a four-stage investigation. First, a genome-wide association study of single nucleotide polymorphisms (SNPs) was done with 754 never smokers (377 matched case-control pairs at Mayo Clinic, Rochester,...

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PMID: 20304703
DOI: 10.1016/S1470-2045(10)70042-5
PMCID: PMC2945218

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GPC5

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