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Article

The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila.

Genetics - 1 Jul 2018

Drelon Coralie, Belalcazar Helen M, Secombe Julie

Abstract excerpt

Regulated gene expression is necessary for developmental and homeostatic processes. The KDM5 family of transcriptional regulators are histone H3 lysine 4 demethylases that can function through both demethylase-dependent and -independent mechanisms. While loss and overexpression of KDM5 proteins are linked to intellectual disability and cancer, respectively, their normal developmental functions remain less...

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Identifiers

PMID: 29764901
DOI: 10.1534/genetics.118.301004
PMCID: PMC6028249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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