Gene regulation by the lysine demethylase KDM4A in Drosophila.

doi:10.1016/j.ydbio.2012.11.011

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Gene regulation by the lysine demethylase KDM4A in Drosophila.

Developmental biology - 15 Jan 2013

Crona Filip, Dahlberg Olle, Lundberg Lina E, Larsson Jan, Mannervik Mattias

Abstract excerpt

Lysine methylation of histones is associated with both transcriptionally active chromatin and with silent chromatin, depending on what residue is modified. Histone methyltransferases and demethylases ensure that histone methylations are dynamic and can vary depending on cell cycle- or developmental stage. KDM4A demethylates H3K36me3, a modification enriched in the 3' end of active genes. The genomic targets and...

Topics

Alleles
Animals
Chromobox Protein Homolog 5
Chromosomal Proteins, Non-Histone
Drosophila Proteins
Drosophila melanogaster
Gene Expression Regulation, Developmental
Histone Demethylases
Histones
Lysine
Male
Methylation

Source

Open in PubMed

Identifiers

PMID: 23195220
DOI: 10.1016/j.ydbio.2012.11.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics