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Article

The histone demethylase Dmel\Kdm4A controls genes required for life span and male-specific sex determination in Drosophila.

Gene - 15 Jan 2010

Lorbeck Meridith T, Singh Neetu, Zervos Ashley, Dhatta Madhusmita, Lapchenko Maria, Yang Chen, Elefant Felice

Abstract excerpt

Histone methylation plays an important role in regulating chromatin-mediated gene control and epigenetic-based memory systems that direct cell fate. Enzymes termed histone demethylases directly remove the methyl marks from histones, thus contributing to a dynamically regulated histone methylated genome; however, the biological functions of these newly identified enzymes remain unclear. The JMJD2A-D family belongs...

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Identifiers

PMID: 19786080
DOI: 10.1016/j.gene.2009.09.007
PMCID: PMC2795090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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