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Article

Global genetic differentiation of complex traits shaped by natural selection in humans.

Nature communications - 14 May 2018

Guo Jing, Wu Yang, Zhu Zhihong, Zheng Zhili, Trzaskowski Maciej, Zeng Jian, Robinson Matthew R, Visscher Peter M, Yang Jian

Abstract excerpt

There are mean differences in complex traits among global human populations. We hypothesize that part of the phenotypic differentiation is due to natural selection. To address this hypothesis, we assess the differentiation in allele frequencies of trait-associated SNPs among African, Eastern Asian, and European populations for ten complex traits using data of large sample size (up to ~405,000). We show that SNPs...

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Identifiers

PMID: 29760457
DOI: 10.1038/s41467-018-04191-y
PMCID: PMC5951811

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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