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Article

Quantifying genetic heterogeneity between continental populations for human height and body mass index.

Scientific reports - 4 Mar 2021

Guo Jing, Bakshi Andrew, Wang Ying, Jiang Longda, Yengo Loic, Goddard Michael E, Visscher Peter M, Yang Jian

Abstract excerpt

Genome-wide association studies (GWAS) in samples of European ancestry have identified thousands of genetic variants associated with complex traits in humans. However, it remains largely unclear whether these associations can be used in non-European populations. Here, we seek to quantify the proportion of genetic variation for a complex trait shared between continental populations. We estimated the...

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Identifiers

PMID: 33664403
DOI: 10.1038/s41598-021-84739-z
PMCID: PMC7933291

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