Allele frequency differentiation at height-associated SNPs among continental human populations.

Abstract excerpt

Methods to detect polygenic adaptation have recently been shown to be sensitive to uncorrected stratification in GWAS, thereby casting doubts on whether polygenic adaptation is prevalent among humans. Consistent with a signal of adaptation at human height loci, the mean FST among African, East Asian, and European populations was shown to be significantly higher at height-associated SNPs than that at...

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