Article
Next-generation sequencing identified somatic alterations that may underlie the etiology of Chinese papillary thyroid carcinoma.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 May 2023
Yang Chuanjia, Gong Jian, Xu Weixue, Liu Zhen, Cui Dongxu
Abstract excerpt
To better understand the etiology of papillary thyroid carcinoma, we did next-generation sequencing for the exomes and transcriptomes of a Chinese cohort of 28 pairs of DNA and RNA samples extracted from papillary thyroid carcinoma tumors and adjacent normal thyroid samples. The Chinese papillary thyroid carcinoma tumors harbored somatic mutations in the known driver genes, such as KRAS, TP53, BRAF, ERBB2 , and...
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