Article
Somatic Mutation Profiling of Papillary Thyroid Carcinomas by Whole-exome Sequencing and Its Relationship with Clinical Characteristics.
International journal of medical sciences - 1 Jan 2021
Qi Tingyue, Rong Xin, Feng Qingling, Sun Hongguang, Cao Haiyan, Yang Yan, Feng Hao, Zhu Linhai, Wang Lei, Du Qiu
Abstract excerpt
The incidence of papillary thyroid carcinomas (PTCs) has increased rapidly during the past several decades. Until now, the mechanisms underlying the tumorigenesis of PTCs have remained largely unknown. Next-generation-sequencing (NGS) provides new ways to investigate the molecular pathogenesis of PTCs. To characterize the somatic alterations associated with PTCs, we performed whole-exome sequencing (WES) of PTCs...
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