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Article

Cellular senescence links aging and diabetes in cardiovascular disease

11 May 2018

Abstract excerpt

Aging is a powerful independent risk factor for cardiovascular diseases such as atherosclerosis and heart failure. Concomitant diabetes mellitus strongly reinforces this effect of aging on cardiovascular disease. Cellular senescence is a fundamental mechanism of aging and appears to play a crucial role in the onset and prognosis of cardiovascular disease in the context of both aging and diabetes. Senescent cells...

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PMID: 29750567
DOI: 10.1152/ajpheart.00287.2018

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