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Cellular Senescence in Ageing, Age-Related Disease and Longevity

18 Dec 2013

Abstract excerpt

Cellular senescence is the state of permanent inhibition of cell proliferation. Senescent cells are characterized by several features including increased activity of senescence-associated β-galactosidase (SA-β-GAL) and senescenceassociated secretory phenotype (SASP). In vitro, 2 types of senescence have been described. One is telomere-dependent replicative senescence and the second is stress-induced premature...

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Share to Genetics, Aging, and Longevity in Model Organisms
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PMID: 24350932
DOI: 10.2174/1570161111666131219094045

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