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Cellular senescence and cardiovascular diseases: moving to the “heart” of the problem

1 Sept 2022

Abstract excerpt

Cardiovascular diseases (CVDs) constitute the prime cause of global mortality, with an immense impact on patient quality of life and disability. Clinical evidence has revealed a strong connection between cellular senescence and worse cardiac outcomes in the majority of CVDs concerning both ischemic and nonischemic cardiomyopathies. Cellular senescence is characterized by cell cycle arrest accompanied by...

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PMID: 36049114
DOI: 10.1152/physrev.00007.2022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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