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Cellular Senescence in Cardiovascular Diseases: Potential Age-Related Mechanisms and Implications for Treatment

1 Jan 2013

Abstract excerpt

The aging process is associated with a loss of complexity in the dynamics of physiological systems that reduce the ability to adapt to stress, causing frailty and/or age-related diseases. At the cellular level, proliferative and/or oxidative-stress induced cell senescence associated with a pro-inflammatory state may greatly contribute to age-associated impaired tissue and organ functions. Senescence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23061728
DOI: 10.2174/1381612811319090018

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